Sytheon Patents Isosorbide Esters for Skin Diseases, Enters Dermatological Market

Sytheon inventors have discovered certain esters of isosorbide can modify and regulate the expression of genes, genetic networks, and cellular pathways in the skin. The company has patented this invention for the dermatology market.

Assigned to Sytheon, U.S. Patent 10,597,402 discloses, “compositions and methods for restoring epidermal integrity and function and treating dermatol­ogical diseases.” According to the company, these esters can be used to improve and/or address defects or imbalances in keratinocyte differen­tiation.

They also can repair skin barrier building and defend its functioning and integrity, improving overall stratum corneum development, structure, and architecture. Furthermore, the esters are reportedly effective for combating, mitigating, and/or preventing the manifestation of diseased conditions, defects, or imbalances in the skin.

Securing this patent, Sytheon stakes claim through its sister company, Symbionyx Phamaceu­ticals Inc., in the dermatol­ogical market to treat diseases caused by autoimmune imbalances.