Sytenol® A Bakuchiol
The True Natural Alternative to Retinol
Sytenol® A, derived from the Babchi seeds, is scientifically validated to harness the transformative benefits of retinol without the potential for irritation and sensitization. Offering a gentle yet transformative technology for addressing signs of aging and acne while safeguarding skin from environmental aggressors to promote a radiant, youthful complexion.
Ideal for acne-prone skin and anti-aging formulas, including those with sensitive skin. Safe for use during the day.
Sytenol® A At A Glance
Sytenol® A
at a Glance
INCI
Bakuchiol
Use Level
0.5 to 1%
Origin
Plant, >99% Pure Well-defined Compound
- Photoaging:
About 20% reduction in wrinkle surface area after 12 weeks for both active ingredients - Hyperpigmentation:
59% reduction in hyperpigmentation after 12 weeks for Sytenol® A Bakuchiol whereas 44% for Retinol - Skin Scaling & Stinging:
The retinol users reported more facial skin scaling and stinging than Sytenol® A Bakuchiol by a factor of 3 to 5 folds more in a 12-week study. - Globally approved, including China
- Better tolerability profile than retinol
- Clinically proven to address multiple signs of aging
- Similar result to retinol in its ability to improve photoaging attributes
- Functional analog of retinol
- Photochemically stable
- Easy to formulate for both day and night treatments
Key Attributes
In a study published in the British Journal of Dermatology, UC Davis dermatologists concluded that Sytenol® A could effectively improve the signs of aging in the skin, making it one alternative that’s better tolerated by the skin than retinol. Sytenol® A is a well-defined compound that’s easy to formulate with and stays stable over time.
Globally approved. Nature certified. REACH registered. Patented product.
Clinically Proven to Mitigate Signs of Acne
Sytenol® A can be used alone or in combination with Salicylic Acid to significantly improve the reduction of comedones and erythema.
Maintains Integrity of Skin Lipids
Sytenol® A helps control excess sebum production and provides relief to acne-affected skin
Defense Against Oxidative Stress
Sytenol® A is a broad-spectrum antioxidant that helps prevent lipid oxidation on the skin and stimulates the antioxidant defense system, making it ideal for both acne-prone and aging skin types.
Defense Against Inflammation
Skin and inflammation are critically linked. The inflammation-induced aging process involves a complex chain of events that can lead to reduced barrier function and collagen breakdown. Sytenol® A controls inflammation by inhibiting pro-inflammatory genes and enzymes.
A True Retinol Alternative
Sytenol® A mimics the effects of Retinol to decrease wrinkle surface area and hyperpigmentation, without the irritation, safety, and stability issues of Retinol.
Reduces Multiple Signs of Visible Skin Aging
Sytenol® A showed significant improvement in fine lines and wrinkles, pigmentation, skin elasticity, firmness and overall photo-damage without irritation.
Skin Concerns
ACNE PREVENTION
Anti-Acne
DAY AND NIGHT
Anti-Aging
SKIN PROTECTION
UV Damage Prevention & Repair
FAQs
The plant where Bakuchiol comes from, the Psoralea corylifolia, is endemic to certain Asian countries such as India Himalayan regions of Pakistan and China. It is a wild species that has been used in Ayurvedic medicine for centuries.
Psoralea corylifolia is a wild leguminous plant that grows from 60-100 cm and takes 7 to 8 months to reach maturity.
The seeds that contain Bakuchiol are wild harvested between December and January.
Yes, Bakuchiol is natural. It is obtained from the babchi seeds found in the Psoralea corylifolia plant through a monomolecular extraction, which means we extract only one molecule, over 99% of Bakuchiol.
Babchi is the traditional name of the seeds of the plant Psoralea corylifolia. Babchi oil is not pure Bakuchiol! Our laboratory measured between 1.6% and 12.1% Bakuchiol content in babchi oils sold through e-commerce platforms. But more importantly, without proper purification, babchi oil naturally contains psoralens, photomutagenic and photocarcinogenic compounds that can be harmful for the skin. We do not recommend the use of babchi oils for cosmetic purposes.
Bakuchiol is an active ingredient that's not meant to be used on the skin in its pure form. However, you can find Bakuchiol in finished products. If you have any doubts whether the product contains Bakuchiol or not, feel free to contact us.
Yes, Bakuchiol is vegan. It is obtained through a vegetable source that does not contain any animal-based raw material.
Bakuchiol is obtained from the plant, Psoralea corylifolia, that grows in India and Himalayan regions of Pakistan and China.
In a 2019 safety assessment taking into account all toxicological data available, a finished product containing 1% Bakuchiol with over 99% purity has been considered safe for topical application on the face.
Traditionally, Bakuchiol is pronounced “buh-koo-chee-all."
Bakuchiol is a retinol-alternative. It stimulates key anti-aging genes like retinoid binding and metabolizing genes. It is also an antioxidant, a stimulator of collagens and an inhibitor of lipo-peroxidation.
Bakuchiol is not retinol nor a retinoid compound because the chemical structure is different. However, it is considered a retinol-alternative as it functions like retinol without the drawbacks. Bakuchiol can be used during the day and is better tolerated by the skin.
Clinical studies have shown that Bakuchiol significantly reduces hyperpigmentation and wrinkles. In particular, in the 2018 publication of the British Journal of Dermatolgy, the University of California concluded that Bakuchiol is comparable with retinol in reducing photoaging but it is better tolerated by the skin.
Bakuchiol helps to reduce inflammation, control the overpopulation of bacteria, maintain the integrity of the sebum and reduces hyperkeratinization. Clinical studies have shown Bakuchiol is more efficient than salicylic acid in reducing acne.
A product formulated with 1% Bakuchiol can be used on the face twice a day.
No, Bakuchiol is photostable, so it can be used during the day.
There is no data on reproductive and developmental effects, so using Bakuchiol is not recommended for pregnant women.
Bakuchiol is extracted from babchi seeds. Therefore, the pure raw material is a yellow to yellowish brown liquid.
No Bakuchiol is oil-soluble. However, you can incorporate 1% Sytenol® A into a water-based serum with the correct amount of surfactants.
Other Ingredients
Isosorbide Dicaprylate
Hydra Synol® DOI
A smart lipophilic skin hydrator & barrier builder
Hexylresorcinol
Synovea® HR
The gold standard in skin brightening & even toning
Ethyl Linoleate
Synovea® EL
A synergist with multiple skin benefits
Isosorbide Dicaprylate | Bakuchiol | Ethyl Linoleate
Asyntra® D-Stress
Destress your skin