Synoxyl® AZ

Acetyl Zingerone

Microbiome Friendly, 24/7 Prevention & Repair of Skin Damage

Synoxyl® AZ is a multi-targeted antiaging molecule designed to counteract aging before it happens and to reverse key signs of photo-damaged skin including pigmentation. AZ prevents skin damage and nurtures skin’s own ability to maintain the integrity of the ECM for optimal health and appearance throughout life. AZ thus provides a translational step forward towards development of a truly efficacious molecule to treat or prevent the consequences of intrinsic and extrinsic skin aging.

Synoxyl® AZ at a Glance

Synoxyl® AZ

 at a Glance

INCI

Acetyl Zingerone

Use Level

0.5 to 1%

Origin

Organic Synthesis

Key Results from Clinical Studies

  • Significant reduction in wrinkle severity (>25%) and volume in 4 weeks as compared to placebo
  • Significant reduction in pigment intensity (>25%) in 4 weeks as compared to placebo
  • Maintains skin microbiome diversity with >20% increase in Staph epidermidis
  • Significant reduction (40%) in skin redness induced by UV challenge test

Characteristics

  • All-in-one: antioxidant, quencher and selective chelator
  • Reduces both immediate and delayed skin damage
  • Non-sacrificing stable antioxidant as compared to conventional antioxidants
  • Elevates biological skin defenses

Formulation Guide

Understand how to use Synoxyl® AZ in your formula by requesting the formulation guide.

Key Attributes

Synoxyl® AZ provides a translational step forward in developing a more efficacious molecule to treat or prevent the signs of both natural and environmental skin aging.
Globally approved except China. Work is under way to get China approval. REACH registered. Patented product.

Synoxyl® AZ provides a translational step forward in developing a more efficacious molecule to treat or prevent the signs of both natural and environmental skin aging.
Globally approved except China.
Work is under way to get China approval.
REACH registered.
Patented product.

Applications

SKIN DETOX

Anti-Pollution

PHOTO-AGING REPAIR

Before & After Sun

SKIN PROTECTION

Sun Preparation & Daily Skin Care

Publications

Antioxidants, 12, 278, 2023

J Srivastava. MM Young, VK Yadav, PR Phadatare, TA Meyer, RK Chaudhuri, S Premi

J Cosmetic Dermatology, 20(1):166-173, 2021

S Dhaliwal, I Rybak, A Pourang, W Burney, K Haas, S Sandhu, R Crawford, R Sivamani

Other Ingredients

Trimethoxybenzylidene Pentanedione

Synoxyl® HSS

Synoxyl HSS

Solution to make Hawaii-compliant sunscreens

Isosorbide Dicaprylate

Hydra Synol® DOI

A smart lipophilic skin hydrator & barrier builder

Ethyl Linoleate

Synovea® EL

A synergist with multiple skin benefits

Isosorbide Dicaprylate | Bakuchiol | Ethyl Linoleate

Asyntra® D-Stress

Destress your skin