Synoxyl® AZ

Acetyl Zingerone

Microbiome Friendly, 24/7 Prevention & Repair of Skin Damage

Synoxyl® AZ is a multi-targeted antiaging molecule designed to counteract aging before it happens and to reverse key signs of photo-damaged skin including pigmentation. AZ prevents skin damage and nurtures skin’s own ability to maintain the integrity of the ECM for optimal health and appearance throughout life. AZ thus provides a translational step forward towards development of a truly efficacious molecule to treat or prevent the consequences of intrinsic and extrinsic skin aging.

Synoxyl® AZ at a Glance

Synoxyl® AZ

at a Glance

INCI

Acetyl Zingerone

Use Level

0.5 to 1%

Origin

Organic Synthesis

Key Results from Clinical Studies

Significant reduction in wrinkle severity (>25%) and volume in 4 weeks as compared to placebo
Significant reduction in pigment intensity (>25%) in 4 weeks as compared to placebo
Maintains skin microbiome diversity with >20% increase in Staph epidermidis
Significant reduction (40%) in skin redness induced by UV challenge test

Characteristics

All-in-one: antioxidant, quencher and selective chelator
Reduces both immediate and delayed skin damage
Non-sacrificing stable antioxidant as compared to conventional antioxidants
Elevates biological skin defenses

Formulation Guide

Understand how to use Synoxyl® AZ in your formula by requesting the formulation guide.

Key Attributes

Synoxyl® AZ provides a translational step forward in developing a more efficacious molecule to treat or prevent the signs of both natural and environmental skin aging.
Globally approved except China. Work-in-progress for China approval. REACH registered. Patented product.

Synoxyl® AZ provides a translational step forward in developing a more efficacious molecule to treat or prevent the signs of both natural and environmental skin aging.
Globally approved except China.
Work is under way to get China approval.
REACH registered.
Patented product.

Powerful Omni Antioxidant

Synoxyl® AZ has the unique ability to scavenge and quench reactive species, and selectively chelate iron. This makes it the first-in-the-industry omni-antioxidant product.

Strong Skin Defense

Placebo-controlled clinical studies revealed Synoxyl® AZ caused significant improvement in skin defense and the reduction of wrinkles, pigmentation and skin redness in photo-aged skin without using sunscreens.

Photochemically Stable Antioxidant

Unlike many conventional antioxidants, Synoxyl® AZ is a photochemically stable antioxidant. This means it can’t be easily broken down or degraded by exposure to UV light or other forms of radiation.

Effective Skin Rejuvenation

Synoxyl® AZ balances skin microbiome diversity and stimulates skin-friendly Staphylococcus epidermidis by >20%. This keeps your customers’ skin healthy and prevents skin conditions like acne, eczema and psoriasis.

Reliable Skin Protection

Synoxyl® AZ is the first in the industry that prevents cyclobutane pyrimidine dimers (CPDs), reducing immediate and delayed skin damage from UV radiation.