Synastol® TC

Terminalia Chebula Fruit Extract

The Holistic Solution to Pollution & Blue Light- Induced Skin Damage with Anti-Aging Benefits

Synastol® TC is a standardized and well-defined extract of the edible hyperfruit Terminalia chebula. As a multi-functional and global anti-aging ingredient, it clinically improves the appearance of fine lines, wrinkles and eye areas. It also provides a true natural solution to pollution and blue light-induced skin damage. When taken as an oral supplement, it provides skin benefits while improving gut homeostasis.  

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Synastol® TC at a Glance

Synastol® TC

 at a Glance

INCI

Terminalia Chebula Fruit Extract

Use Level

0.5 to 1%

Origin

Plant, Direct Extraction

Key Results from Clinical Studies
  • Significant improvement in:
    • Aging parameters within 4 weeks and continued improvement until week 12
    • Overall eye appearance
    • Pigmentation attributes
    • Significant reduction in under-eye dark circles
  • Oral supplement results:
    • Greater alpha diversity and increased amounts of favorable gut bacteria and phages
    • 33% decrease in sebum excretion rate 
    • Statistically significant decrease in cheek erythema 
    • Statistically significant decrease in wrinkles
Characteristics
  • Supercharged antioxidant with multifunctional benefits
  • Standardized fruit extract with defined (>60%) bioactive
  • Photostable cascading antioxidant without prooxidant activity
Formulation Guide

Understand how to use Synastol® TC in your formula by requesting the formulation guide.

Key Attributes

As a broad-action antioxidant with an ORAC value superior to major hyperfruits, Synastol® TC has been shown to reduce the formation of reactive oxygen species (ROS) and lipid peroxides caused by sun, pollution and blue light. It also reduces pollution-induced pro-inflammatory biomarkers IL-6 and IL-8.

Globally approved. COSMOS natural. REACH registered.

As a broad-action antioxidant with an ORAC value superior to major hyperfruits, Synastol® TC has been shown to reduce the formation of reactive oxygen species (ROS) and lipid peroxides caused by sun, pollution and blue light. It also reduces pollution-induced pro-inflammatory biomarkers IL-6 and IL-8.
Globally approved.
COSMOS natural.
REACH registered.

Applications

SKIN DETOX AND BLUE LIGHT PROTECTION

Anti-Pollution

DAY AND NIGHT

Anti-Aging

Anti Aging

SUPERFRUIT WITH AYURVEDIC CLAIMS

Green Cosmetic Skincare

BEAUTY FROM THE INSIDE OUT

Oral Supplement for Skin Care

Oral Supplement for Skin Care

ELEVATING MICROBIOME DIVERSITY

Oral Supplement for Regulating Gut Health

Oral Supplement for Regulating Gut Health

Publications

Int J Cosmet Sci., doi: 10.1111/ics.12858, 2023

Bogdanowicz P, Roullet N, Bensadoun P, Bessou-Touya S, Lemaitre JM, Duplan H

J. Clinical Medicine, 12(4), 1591, 2023

M Chakkalakal, A Pan, D Nadora, N Gahoonia, RK Chaudhuri, W Burney, S Thacker, A Shakhbazova, C Subramanyam, CJ Chambers, RK Sivamani

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