Publications

At Sytheon, we rigorously test all of our ingredients – leaving no questions unanswered. Read our research in various publications to discover how our ingredients can meet the needs of your customers.

Groundbreaking Research on High-Performing Actives

Explore our research that supports each active we offer.

Synoxyl® AZ (Acetyl Zingerone)

Prospective randomized double-blind comparative study of topical acetyl zingerone with tetrahexyldecyl ascorbate versus tetrahexyldecyl ascorbate alone on facial photoaging

Cosmet Dermatol. 2024; 00: 1-11.

N Afzal, N Nguyen, M Min, C Egli, B Ed, S Afzal, RK Chaudhuri, WA Burney, RK Sivamani

Synoxyl® AZ (Acetyl Zingerone)

Acetyl Zingerone: A Photostable Multifunctional Skincare Ingredient That Combats Features of Intrinsic and Extrinsic Skin Aging

Antioxidants, 12(6):1168, 2023

TA Meyer, WR Swindell, RK Chaudhuri

Synoxyl® AZ (Acetyl Zingerone)

The Role of Acetyl Zingerone and Its Derivatives in Inhibiting UV-Induced, Incident, and Delayed Cyclobutane Pyrimidine Dimers

Antioxidants, 12(2), 278, 2023

J Srivastava. MM Young, VK Yadav, PR Phadatare, TA Meyer, RK Chaudhuri, S Premi

Synoxyl® AZ (Acetyl Zingerone)

Tetrahexyldecyl Ascorbate (THDC) Degrades Rapidly under Oxidative Stress but Can Be Stabilized by Acetyl Zingerone to Enhance Collagen Production and Antioxidant Effects

International J Molecular Sciences, 22:8756, 2021

WS Swindell, M Randhawa, G Quijas, K Bojanowski, RK Chaudhuri

Synoxyl® AZ (Acetyl Zingerone)

Randomized Double-Blind Vehicle Controlled Study of the Effects of Topical Acetyl Zingerone on Photoaging

J Cosmetic Dermatology, 20(1):166-173, 2021

S Dhaliwal, I Rybak, A Pourang, W Burney, K Haas, S Sandhu, R Crawford, R Sivamani

Synoxyl® AZ (Acetyl Zingerone)

Acetyl zingerone: An efficacious multifunctional ingredient for continued protection against ongoing DNA damage in melanocytes after sun exposure ends

International J Cosmetic Science, 42(1):36-45, 2020

RK Chaudhuri, T Meyer, S Premi, D Brash

Synoxyl® AZ (Acetyl Zingerone)

A Zingerone Analog, Acetyl Zingerone, Bolsters Matrisome Synthesis, Inhibits Matrix Metallopeptidases, and Represses IL-17A Target Gene Expression

J Invest Dermatol, 140:602-614, 2020

WR Swindell, K Bojanowski, RK Chaudhuri

Synoxyl® AZ (Acetyl Zingerone)

Omni Antioxidant: Acetyl Zingerone Scavenges/Quenches Reactive Species, Selectively Chelates Iron

Cosmetics & Toiletries, Article # 21835862, 2020

T Meyer, RK Chaudhuri