New publication on Synoxyl® HSS (INCI: Trimethoxybenzylidene Pentanedione)

In a recent issue of the peer-reviewed journal, International Journal of Cosmetic Science, the authors reported the findings of a study conducted with Synoxyl® HSS. Results of this study shows that Synoxyl® HSS is an excellent photostabilizer of Avobenzone in sunscreen formulations and the performance is at least equal if not better than the currently available photostabilizers and also provides a 50% in-vivo SPF boosting. The ability of Synoxyl® HSS to stabilize avobenzone under ultraviolet (UV) light exposure was shown both in formulated products and in solution. A comparative stability study incorporating various combinations of avobenzone, Synoxyl® HSS (vs. three commercial photostabilizers) and UVB sunscreens clearly showed Synoxyl® HSS to be a very effective stabilizer. The photostabilizing effect of Synoxyl® HSS arises from triplet-state energy transfer from avobenzone to Synoxyl® HSS and through light-induced reactions that preserve the main chromophores. Interestingly, a 50% in vivo SPF boosting was observed when Synoxyl® HSS was used with organic and inorganic sunscreens when alone it has no contribution to SPF. Synoxyl® HSS-containing sunscreen formulations clearly showed a critical wavelength of well over 370 nm and can thus be categorized as broad-spectrum sunscreens. The optical properties of Synoxyl® HSS were estimated experimentally and supported by time-dependent density functional theory (TD-DFT) calculations.

For more information, please review or ask for a copy of this publication:

3-(3,4,5-Trimethoxybenzylidene)-2,4-pentanedione: Design of a novel photostabilizer with in vivo SPF boosting properties and its use in developing broad-spectrum sunscreen formulations, RK Chaudhuri, MA Ollengo, P Singh and BS Martincigh, Version of Record online: International J of Cosmetic Science, 29 JUN 2016 | DOI: 10.1111/ics.12344

Sytheon recently published breakthrough research on acetyl zingerone and tetrahexyldecyl ascorbate’s effectiveness on skin photoaging.
Synastol® TC is a natural, safe ingredient that can now be used as a nutritional supplement, providing holistic benefits for customers.
Acetyl Zingerone is a perfect active for your next sun care product that protects the skin before, during and after sun exposure. Here’s how.
Hexylresorcinol does not pose the same dangers as resorcinol. Keep reading to understand the differences between these ingredients.
Here are the top five skin care ingredient trends that forward-thinking brands should capitalize on in 2024.
Dr. Ratan K. Chaudhuri is an innovator passionate about helping others, which led to a career in personal care and starting Sytheon in 2006.
Clinical Study: Synoxyl® AZ & VitaSynol® C on Photoaging

Clinical Study: Synoxyl® AZ & VitaSynol® C on Photoaging

In a recent article published in the Journal of Cosmetic Dermatology, researchers evaluated the effects of Synoxyl® AZ (acetyl zingerone,...

by Dr. Ratan K. ChaudhuriApril 15, 2024
Read More
New Application: Synastol® TC (Terminalia Chebula Fruit Extract) Now Available as a Nutritional Supplement

New Application: Synastol® TC (Terminalia Chebula Fruit Extract) Now Available as a Nutritional Supplement

Get Your Gut in the Game of Skin Beauty – The Science Behind Standardized Terminalia Chebula Fruit Extract for Delivering...

by Dr. Ratan K. ChaudhuriFebruary 20, 2024
Read More
How to Incorporate Acetyl Zingerone (Synoxyl® AZ) Into Your Sun Care Product Line

How to Incorporate Acetyl Zingerone (Synoxyl® AZ) Into Your Sun Care Product Line

Most consumers are aware of the dangers of sun exposure and have incorporated sunscreen into their routine as a result....

by Dr. Ratan K. ChaudhuriFebruary 8, 2024
Read More
Hexylresorcinol vs. Resorcinol: What’s the Difference?

Hexylresorcinol vs. Resorcinol: What’s the Difference?

Some beauty brands avoid using hexylresorcinol in their skin care products due to a misconception that it is closely related...

by Dr. Ratan K. ChaudhuriJanuary 24, 2024
Read More
Top 5 Skin Care Ingredient Trends for 2024

Top 5 Skin Care Ingredient Trends for 2024

What are your customers asking for in skin care products, and how can you respond to those demands? In this...

by Dr. Ratan K. ChaudhuriDecember 15, 2023
Read More
Top 6 Safe & High-Performing Skin Lightening Ingredients

Top 6 Safe & High-Performing Skin Lightening Ingredients

Consumers are always looking for new ways to promote the health and appearance of their skin. For those asking for...

by Dr. Ratan K. ChaudhuriNovember 14, 2023
Read More