New publication on Synoxyl® HSS (INCI: Trimethoxybenzylidene Pentanedione)

In a recent issue of the peer-reviewed journal, International Journal of Cosmetic Science, the authors reported the findings of a study conducted with Synoxyl® HSS. Results of this study shows that Synoxyl® HSS is an excellent photostabilizer of Avobenzone in sunscreen formulations and the performance is at least equal if not better than the currently available photostabilizers and also provides a 50% in-vivo SPF boosting. The ability of Synoxyl® HSS to stabilize avobenzone under ultraviolet (UV) light exposure was shown both in formulated products and in solution. A comparative stability study incorporating various combinations of avobenzone, Synoxyl® HSS (vs. three commercial photostabilizers) and UVB sunscreens clearly showed Synoxyl® HSS to be a very effective stabilizer. The photostabilizing effect of Synoxyl® HSS arises from triplet-state energy transfer from avobenzone to Synoxyl® HSS and through light-induced reactions that preserve the main chromophores. Interestingly, a 50% in vivo SPF boosting was observed when Synoxyl® HSS was used with organic and inorganic sunscreens when alone it has no contribution to SPF. Synoxyl® HSS-containing sunscreen formulations clearly showed a critical wavelength of well over 370 nm and can thus be categorized as broad-spectrum sunscreens. The optical properties of Synoxyl® HSS were estimated experimentally and supported by time-dependent density functional theory (TD-DFT) calculations.

For more information, please review or ask for a copy of this publication:

3-(3,4,5-Trimethoxybenzylidene)-2,4-pentanedione: Design of a novel photostabilizer with in vivo SPF boosting properties and its use in developing broad-spectrum sunscreen formulations, RK Chaudhuri, MA Ollengo, P Singh and BS Martincigh, Version of Record online: International J of Cosmetic Science, 29 JUN 2016 | DOI: 10.1111/ics.12344

Synastol® TC (Terminalia Chebula Fruit Extract): A Multifunctional Ingredient for Well-Aging Products

Synastol® TC (Terminalia Chebula Fruit Extract): A Multifunctional Ingredient for Well-Aging Products

In a recent study published in the International Journal of Cosmetic Science, Pierre Fabre researchers evaluated the effects of Synastol®...

by Dr. Ratan K. ChaudhuriSeptember 28, 2023
Read More
Science Meets Beauty: 10 Active Ingredients that Will Enhance Your Skincare Formulation

Science Meets Beauty: 10 Active Ingredients that Will Enhance Your Skincare Formulation

Today’s personal care consumers are vigilant about the ingredients used in their favorite skincare products. They want to know exactly...

by Dr. Ratan K. ChaudhuriSeptember 8, 2023
Read More
Sytheon Takes on Suppliers’ Day in Singapore: Speaking Session & Partner Booth

Sytheon Takes on Suppliers’ Day in Singapore: Speaking Session & Partner Booth

Sytheon, a global supplier of unique and multifunctional active ingredients, is thrilled to announce its participation at this year’s Suppliers’...

by Dr. Ratan K. ChaudhuriSeptember 7, 2023
Read More
Clinical Study: Synastol® TC (Terminalia Chebula Fruit Extract) Supplementation Reduces Wrinkles

Clinical Study: Synastol® TC (Terminalia Chebula Fruit Extract) Supplementation Reduces Wrinkles

In a recent article published in the Journal of Clinical Medicine, Synastol® TC (INCI: Terminalia Chebula Fruit Extract) is the...

by Dr. Ratan K. ChaudhuriJuly 28, 2023
Read More
4 Cosmetic Effects of Synoxyl® AZ (Acetyl Zingerone)

4 Cosmetic Effects of Synoxyl® AZ (Acetyl Zingerone)

Everyone is exposed to environmental pollutants and ultraviolet (UV) rays, which can lead to oxidative stress and skin damage. That’s...

by Dr. Ratan K. ChaudhuriJuly 20, 2023
Read More
Antioxidants Journal Features Review on Synoxyl® AZ (Acetyl Zingerone)

Antioxidants Journal Features Review on Synoxyl® AZ (Acetyl Zingerone)

The versatility of Synoxyl® AZ embodies the definition of a “next generation” skincare ingredient to maintain and augment skin’s beauty...

by Dr. Ratan K. ChaudhuriJuly 13, 2023
Read More