Hydra Synol® DOI

Isosorbide Dicaprylate

A Smart Lipophilic Skin Hydrator & Barrier Builder

Hydra Synol® DOI is a smart skin hydrator and barrier builder that intelligently provides optimum hydration based on skin moisture content/deficit. It’s clinically shown to be very effective in providing long-lasting (>48 hours) and controlled skin hydration.

Hydra Synol® DOI at a Glance

Hydra Synol® DOI

 at a Glance


Isosorbide Dicaprylate

Use Level

2 to 4%


Plant, Green Chemistry

Key Results from Clinical Studies

  • Smart skin hydrator – helps move moisture where it is needed
  • Very effective in providing long-lasting (>48 hours) skin deep and controlled hydration
  • Builds barrier inside out and maintains hydration even after regression period
  • Improves and extends tanning effect in glow products


  • Medium chain fatty acid that acts as source of energy
  • Lipophilic skin hydrator with excellent skin feel
  • Bio-based and biodegradable

Formulation Guide

Understand how to use Hydra Synol® DOI in your formula by requesting the formulation guide.

Key Attributes

Hydra Synol® DOI works by stimulating Aquaporin-3, Tight Junction, Desmosomes and Epidermal Differentiating genes/proteins. It can also be used as a natural and biodegradable alternative to phenyltrimethicone to maximize hair shine. Beyond its active ingredient properties, Hydra Synol® DOI provides a great skin feel and is an excellent solubilizer for UV filters and many lipophilic ingredients.

Globally approved except China. ECOCERT-COSMOS natural. REACH registered. Patented product. Work-in-progress for China approval.



Long-Term Hydration Oils or Lotions



Self Tan


Hair Care


Treating Color Cosmetics

Color Cosmetics


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Ethyl Linoleate

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A synergist with multiple skin benefits

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Synactin® AC

5-in-1 solutions in mitigating acne-affected skin

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