How Bakuchiol Works: Formulation Tips for Brands & Results

Bakuchiol promises great benefits to customers of any skin type. How does it work? Here’s how to formulate with Bakuchiol and what results you can expect.

Bakuchiol, a natural compound isolated from the seeds of the plant Psoralea corylifolia, is a multifunctional active ingredient that can be formulated into many different types of products. Customers love turning to Bakuchiol for its anti-acne and graceful aging applications, especially as a gentle solution for sensitive skin.    

Ready to bring your own twist on Bakuchiol to market? Keep reading for formulation tips that will ensure you deliver the best Bakuchiol product to your customers.

READ MORE | Bakuchiol 101: Everything Skin Care & Beauty Brands Need to Know

How Bakuchiol Works: Formulation Tips for Skin Care Products

A multifunctional ingredient is an ingredient that serves more than one purpose within a product formulation. Bakuchiol is considered a multifunctional ingredient because it delivers more than one benefit to the skin that your product formulation can claim, including:

  • Preventing and repairing UV damage
  • Preventing acne
  • Reducing wrinkles and fine lines

Instead of including three separate actives in your formulation, you would only need one – Bakuchiol – to hit all three of these target claims.

To deliver on these benefits, your brand can formulate Bakuchiol into a serum, cream, lotion, oil, color cosmetic, or hydro-alcoholic spray.

This starts with sourcing the right ingredient. For the most efficacy and safety, Bakuchiol must be over 99% pure. Anything less pure introduces harmful skin sensitizers, unknown ingredients, and residual solvents. Plus, less pure Bakuchiol is unstable and will degrade in your formula over time.

READ MORE | 5 Ways to Tell You Have the Best Bakuchiol

Now that you know what you want to create and have sourced the best grade of Bakuchiol from a trusted supplier, it’s time for formulation. Here are formulation tips for Sytenol® A Bakuchiol, but please refer to the full formulation guide when you request a sample.

  • Sytenol® A Bakuchiol should be used at a level of 0.5 to 1.0% (w/w) of finished formulation.
  • Sytenol® A Bakuchiol can be added directly to the oil phase.
  • Sytenol® A is not miscible with silicones, but both products can be added together into an oil phase.
  • Avoid prolonged heating above 75ºC.
  • Add 0.1% of a chelating agent to overcome coloration issues.
  • The finished product must be acidic with a pH below 6.
  • Protect the finished product from prolong exposure to heat and light to maintain product integrity over time.
  • When using in color cosmetics, pigments need to be coated.
  • Sytenol® A is incompatible with sodium hydroxide due to the phenol OH group.

To deliver even more benefits to your customers, you can formulate a product with Bakuchiol and other active ingredients, including:

Request a Sample of Sytenol® A Bakuchiol

How Bakuchiol Works: Results for Customers

Once you formulate a Bakuchiol product and bring your new skin care product to market, what can your customers expect? These clinical study results are a testament to how well Bakuchiol works:

Preventing & Repairing UV Damage

  • 4-week clinical study published in the Journal of Drugs in Dermatology  
  • 60 volunteers with sensitive mild to moderate photodamaged skin
  • Lotion containing 1% of Sytenol® A Bakuchiol

How It Worked: Investigator-assessed improvement in visual smoothness, tactile smoothness, clarity, radiance, overall appearances, and global aging.  

Preventing Acne

  • 6-week clinical study published in Cosmetics & Toiletries
  • 60 volunteers total with mild to moderate acne comedones
    • 15 volunteers using lotion containing 1% Sytenol® A Bakuchiol
    • 15 volunteers using lotion containing 2% Salicylic acid
    • 15 volunteers using lotion containing 1% Sytenol® A Bakuchiol and 2% Salicylic acid
    • 15 volunteers using placebo

How It Worked: 1% Sytenol® A Bakuchiol lotion reduced acne by 57%, which was more effective than 2% salicylic acid. When 1% Sytenol® A Bakuchiol was combined with 2% salicylic acid, acne was reduced by 67%.

Reducing Wrinkles & Fine Lines

How It Worked: Wrinkle depth was reduced 20%. Also, researchers observed significant improvements in fine lines and wrinkles, elasticity, firmness, and an overall reduction in signs of photoaging.

How Bakuchiol Works Compared to Retinol

The best part? Bakuchiol provides these great results without the skin scaling and stinging that is often associated with retinol, another common ingredient used for similar purposes. A 2019 study with UC Davis Dermatologists validated this reality:

How It Worked: Sytenol® A Bakuchiol and retinol both significantly decreased wrinkle surface area (20%) and hyperpigmentation (59% reduction for Sytenol® A Bakuchiol; 44% for retinol). Retinol users reported more facial skin scaling and stinging by a factor of three to five folds more.

READ MORE | 3 Key Distinctions Between Bakuchiol and Retinol


Bakuchiol is all the rage in the skin care game. Now that you know how it works in your formula and how it works for your customers, it’s time to bring your own future best-selling Bakuchiol product to market.

If you have questions about incorporating Bakuchiol into your skin care line, please contact us. If you’re ready for a sample of Sytenol® A Bakuchiol, please request one here.